Safety of Aspirin for Prevention of Heart Attack/Stroke
Routine Consumption of Aspirin to Prevent Heart
Attacks and
Strokes "A Big Lie" by David
Gutierrez, staff writer
(NaturalNews)
Taking an aspirin a day appears to increase a person's
risk of dangerous
gastric bleeding as much as it decreases their
risk of heart attack or stroke,
researchers have found. "We
don't have good evidence that, for healthy people, the benefits of
long-term
aspirin exceed the risks by an appropriate margin," said lead
researcher Colin Baigent, of the Clinical Trial Service Unit at OxfordUniversity. Health
experts have been recommending for more than a decade that people considered at
increased risk of cardiovascular disease (due to high blood pressure or
cholesterol, obesity, advanced age or other risk factors) take one aspirin pill
per day, as the medicine has been clinically shown to reduce the risk of
serious vascular events in those people. This strategy -- treating people with
no symptoms of heart disease -- is known as "primary prevention." A serious
vascular event is a heart attack, stroke or cardiovascular death. Many health
agencies have shied away from issuing official recommendations, however, such
as the United Kingdom's
National Institute for Health and Clinical Excellence. "There
is no definitive guidance," said Steve Field, chair of the Royal College
of General
Practitioners, "and it makes it bewildering when you have a series of
papers which then hint it would be beneficial to take aspirin." According
to Field, many patients are attracted to aspirin as a way to stave off heart
attacks because the over-the-counter pills are very inexpensive. But the
findings of the newest study, published in The Lancet, suggest that the risks
of aspirin match the benefits in cases of primary prevention. Only in patients
who have already had a heart attack or stroke does the benefit appear to
outweigh the risk. "This
important study does suggest people shouldn't take aspirin unless indicated by
disease," Field said. While
primary prevention recommendations have been based on estimated risks and
benefits of aspirin treatments, the current study actually analyzed the effects
of the treatment in 22 studies involving more than 100,000 participants. Six of
the studies involved 95,000 people with a low to average risk of heart attack or
stroke -- the typical primary prevention population -- and the other 16
involved 17,000 people who had already experienced at least one heart attack or
stroke. In both
groups, taking an aspirin a day decreased the risk of a serious vascular event
by about 20 percent in both men and women. It also increased the risk of
gastric bleeding by about 33 percent. In the
lower-risk group, this came out to five fewer serious vascular events each year
per 10,000 people taking a daily aspirin. It also meant three extra cases of
gastric bleeding, however, and one extra stroke caused by internal bleeding.
This led the researchers to conclude that the risks and benefits of the
treatment were equivalent. The results
might be explained by the fact that people at increased risk of cardiovascular
disease also tend to be at higher risk of gastric bleeding. Because
people who had already experienced a heart attack or stroke had such a
heightened risk of further vascular events, however, the benefits exceeded the
risks in that group -- roughly 150 serious vascular events prevented per year
for every 10,000 people treated, with the same three extra gastric bleeds and
one stroke from bleeding. "Aspirin
is of clear benefit for people who already have cardiovascular disease, but the
latest research does not seem to justify general guidelines advocating the
routine use of aspirin in all healthy individuals above a moderate level of
risk for coronary heart disease," the researchers concluded. "It is
better for doctors to weigh up the benefit and risk of prescribing aspirin on
an individual basis, rather than develop a blanket guideline suggesting
everyone at risk of heart disease is routinely given aspirin," said Ellen
Mason of the British Heart Foundation. Sources for
this story include: news.bbc.co.uk; www.sciencedaily.com.